Methanol → Methyl 6-(4-(2-aminoethyl)phenyl)-6-(3-pyridyl)hex-5-enoate

HRID 22130Notes

Reaction equation

HRID 22130 reaction equation
C([NH:4][CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]([C:21]2[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=2)=[CH:14][CH2:15][CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[CH:9][CH:8]=1)(=O)C.[CH3:27]O>>[NH2:4][CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]([C:21]2[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=2)=[CH:14][CH2:15][CH2:16][CH2:17][C:18]([O:20][CH3:27])=[O:19])=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 887MethanolHCID 537221676-(4-(2-Acetylaminoethyl)-phenyl)-6-(3-pyridyl)hex-5-enoic acid

Product 1

HCID 54161160Methyl 6-(4-(2-aminoethyl)phenyl)-6-(3-pyridyl)hex-5-enoate

Procedure

Prepared by hydrolysis of 6-(4-(2-acetylaminoethyl)-phenyl)-6-(3-pyridyl)hex-5-enoic acid and subsequent esterification with methanol analogously to Example 8b.

Sources & evidence

ORD record
ord-56070f633c464eaa985ccdb7488c56ee
Source dataset
uspto-grants-1995_06
Patent number
US05426119

Reaction notes

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