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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 221314Generated: October 25, 2026

Aniline → N-(2,6-difluoro-phenyl)-2-methyl-6-nitro-benzamide

https://huagongshe.com/reaction/221314

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
Reactant5-Methyl-2-nitrobenzoic acidHCID 18371—
Reactant2,6-DifluoroanilineHCID 79647—
Reactant2-Fluoro-6-nitrobenzoic acidHCID 603758—
ReactantHCID 178456065HCID 178456065—
ProductN-(2,6-difluoro-phenyl)-2-methyl-6-nitro-benzamideHCID 66664557—

Reaction Steps

Compound 118a was prepared following the preparation procedure described above with respect to compound 107, but 2-nitro-5-methylbenzoic acid was substituted for 2-fluoro-6-nitrobenzoic acid and 2,6-difluoroaniline was substituted for aniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08207153B2
Source datasetuspto-grants-2012_06
ORD IDord-d59e7ee8af924843bc6ac5f7c6917486
Source noteuspto-grants-2012_06