HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → tert-Butyl ((1H-benzo[d]imidazol-2-yl)methyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 1,2-Phenylenediamine dihydrochloride | HCID 11990 | — |
| Reactant | tert-butyl N-(cyanomethyl)carbamate | HCID 545844 | — |
| Reactant | HCID 178418582 | HCID 178418582 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | tert-Butyl ((1H-benzo[d]imidazol-2-yl)methyl)carbamate | HCID 11448004 | — |
Reaction Steps
3.32 g of a 30% NaOCH3 solution were added to tert-butyl cyanomethylcarbamate (3 g; 19.21 mmol) in 20 ml of CH3OH, and the mixture was stirred at room temperature for 1 h. After addition of 3.4 g of 1,2-phenylenediamine bishydrochloride, the reaction mixture was stirred further overnight and then added to 100 ml of H2O, and the resulting solid was filtered off and dried in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07105508B1 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-dbbdafbfa47c4854b58d80974b580e8b |
| Source note | uspto-grants-2006_09 |