HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Propanediamine → N-(3-aminopropyl)pyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Propanediamine | HCID 428 | — |
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Product | N-(3-aminopropyl)pyridin-2-amine | HCID 10606924 | 44.9% |
Reaction Steps
2-Bromopyridine (100 g; 0.633 mol) and 1,3-diaminopropane (234.5 g; 3.16 mol) were refluxed for 7 h. After the reaction was complete, the mixture was evaporated, and distillation of the remaining residue under oil pump vacuum afforded 43 g of the required product; ESI-MS [M+H+]=152.15.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07105508B1 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-3afbe37ad4264beca6613610dc777cec |
| Source note | uspto-grants-2006_09 |