Anthranilic Acid → HCID 10920656, compound

HRID 2213159Notes

Reaction equation

HRID 2213159 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH2:11](OC(OCC)OCC)C>>[N:1]1[C:2]2[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=2[C:4](=[O:6])[O:5][CH:11]=1

Participants

3

Reactant 2

HCID 227Anthranilic AcidHCID 31214Ethyl orthoformate

Product 1

HCID 10920656HCID 10920656, compound

Procedure

A mixture of 2-aminobenzoic acid (1 g, 7.29 mmol) and triethylorthoformate (3 mL) was refluxed overnight. The reaction mixture was cooled to room temperature and triturated with 10 mL of hexane. The resulting solid was filtered and further washed with hexane to yield 1.1 g of the expected benzo[d][1,3]oxazin-4-one.

Workup

  1. temperaturewas refluxed overnight
  2. customtriturated with 10 mL of hexane
  3. filtrationThe resulting solid was filtered
  4. washfurther washed with hexane

Sources & evidence

ORD record
ord-45bde706b63d4af48e99767887b3acff
Source dataset
uspto-grants-2006_09
Patent number
US07105537B2

Reaction notes

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