Bromo(phenyl)acetic acid → HCID 10435499, compound

HRID 2213384Notes

Reaction equation

HRID 2213384 reaction equation
[Br:1][CH:2]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[C:3]([OH:5])=O.[NH2:12][CH2:13][CH2:14][CH2:15][N:16]1[CH2:21][CH2:20][CH:19]([C:22]2[CH:23]=[C:24]([NH:28][C:29](=[O:32])[CH2:30][CH3:31])[CH:25]=[CH:26][CH:27]=2)[CH2:18][CH2:17]1>>[Br:1][CH:2]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[C:3]([NH:12][CH2:13][CH2:14][CH2:15][N:16]1[CH2:21][CH2:20][CH:19]([C:22]2[CH:23]=[C:24]([NH:28][C:29](=[O:32])[CH2:30][CH3:31])[CH:25]=[CH:26][CH:27]=2)[CH2:18][CH2:17]1)=[O:5]

Participants

3

Reactant 2

HCID 97919Bromo(phenyl)acetic acidHCID 21957142N-{3-[1-(3-aminopropyl)4-piperidinyl]phenyl}propanamide

Product 1

HCID 10435499HCID 10435499, compound

Procedure

Example 10 was prepared from bromo(phenyl)acetic acid and N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}propanamide according to the procedures described in Scheme 10: ESMS m/e: 486.1 (M+H)+.

Sources & evidence

ORD record
ord-9fe9b0e7d0664afeb9199d5071c735b0
Source dataset
uspto-grants-2006_09
Patent number
US07105544B2

Reaction notes

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