HRID2213388

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID231201

2-phenyl-2-(2,4,6-trimethylphenyl)acetic acid

C17H18O2

HCID21957142

未命名化合物

PRODUCTS

生成物

结构：CCC(=O)Nc1cccc(C2CCN(CCCNC(=O)C(c3ccccc3)c3c(C)cc(C)cc3C)CC2)c1

HCID21957246

未命名化合物

PROCEDURE

实验过程

Example 14 was prepared from mesityl(phenyl)acetic acid and N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}propanamide according to the procedures described in Scheme 9: ESMS m/e: 526.3 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4bf9526193be4fe880d9fc41e84683d4
来源数据集: uspto-grants-2006_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07105544B2
来源说明: uspto-grants-2006_09

反应 SMILES

[C:1]1([CH3:19])[CH:6]=[C:5]([CH3:7])[CH:4]=[C:3]([CH3:8])[C:2]=1[CH:9]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:10](O)=[O:11].[NH2:20][CH2:21][CH2:22][CH2:23][N:24]1[CH2:29][CH2:28][CH:27]([C:30]2[CH:31]=[C:32]([NH:36][C:37](=[O:40])[CH2:38][CH3:39])[CH:33]=[CH:34][CH:35]=2)[CH2:26][CH2:25]1>>[C:1]1([CH3:19])[CH:6]=[C:5]([CH3:7])[CH:4]=[C:3]([CH3:8])[C:2]=1[CH:9]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:10]([NH:20][CH2:21][CH2:22][CH2:23][N:24]1[CH2:29][CH2:28][CH:27]([C:30]2[CH:31]=[C:32]([NH:36][C:37](=[O:40])[CH2:38][CH3:39])[CH:33]=[CH:34][CH:35]=2)[CH2:26][CH2:25]1)=[O:11]