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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2213396Generated: October 31, 2026

2,2-Bis(4-fluorophenyl)acetic acid → N-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-4-methoxyphenyl}-2-methylpropanamide

https://huagongshe.com/reaction/2213396

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Bis(4-fluorophenyl)acetic acidHCID 13511684—
ReactantN-{3-[1-(3-aminopropyl)-4-piperidinyl]-4-methoxyphenyl}-2-methylpropanamideHCID 21957209—
ProductN-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-4-methoxyphenyl}-2-methylpropanamideHCID 21957179—

Reaction Steps

Example 23 was prepared from bis(4-fluorophenyl)acetic acid and N-{3-[1-(3-aminopropyl)-4-piperidinyl]-4-methoxyphenyl}-2-methylpropanamide according to the procedures described in Scheme 9: ESMS m/e: 564.4 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07105544B2
Source datasetuspto-grants-2006_09
ORD IDord-8ddc0e79af1c428abd325c6882f8b5e2
Source noteuspto-grants-2006_09