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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2213429Generated: October 27, 2026

1-(p-Chlorophenyl)cyclobutanecarboxylic acid → 1-(4-chlorophenyl)-N-(3-{4-[3-(propionylamino)phenyl]-1-piperidinyl}propyl)cyclobutanecarboxamide

https://huagongshe.com/reaction/2213429

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(p-Chlorophenyl)cyclobutanecarboxylic acidHCID 602761—
ReactantN-{3-[1-(3-aminopropyl)4-piperidinyl]phenyl}propanamideHCID 21957142—
Product1-(4-chlorophenyl)-N-(3-{4-[3-(propionylamino)phenyl]-1-piperidinyl}propyl)cyclobutanecarboxamideHCID 21957192—

Reaction Steps

Example 58 was prepared from 1-(4-chlorophenyl)cyclobutanecarboxylic acid and N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}propanamide according to the procedures described in Scheme 10: ESMS m/e: 482.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07105544B2
Source datasetuspto-grants-2006_09
ORD IDord-238baf35ade145df900a302485e7a207
Source noteuspto-grants-2006_09