HRID2213481

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID68992

Triphenylacetic acid

C20H16O2

HCID21957166

未命名化合物

PRODUCTS

生成物

结构：O=C(Nc1cccc(C2CCN(CCCNC(=O)C(c3ccccc3)(c3ccccc3)c3ccccc3)CC2)c1)C1CC1

HCID21957225

未命名化合物

PROCEDURE

实验过程

Example 114 was prepared from triphenylacetic acid and N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}cyclopropanecarboxamide according to the procedures described in Scheme 10: ESMS m/e: 572.3 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-66859e91406c4e0fa428c48b27cbd7f3
来源数据集: uspto-grants-2006_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07105544B2
来源说明: uspto-grants-2006_09

反应 SMILES

[C:1]1([C:7]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8](O)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:23][CH2:24][CH2:25][CH2:26][N:27]1[CH2:32][CH2:31][CH:30]([C:33]2[CH:34]=[C:35]([NH:39][C:40]([CH:42]3[CH2:44][CH2:43]3)=[O:41])[CH:36]=[CH:37][CH:38]=2)[CH2:29][CH2:28]1>>[C:17]1([C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:8]([NH:23][CH2:24][CH2:25][CH2:26][N:27]2[CH2:32][CH2:31][CH:30]([C:33]3[CH:34]=[C:35]([NH:39][C:40]([CH:42]4[CH2:44][CH2:43]4)=[O:41])[CH:36]=[CH:37][CH:38]=3)[CH2:29][CH2:28]2)=[O:9])[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1