4-(Dimethylamino)Benzaldehyde → 4-(((4-Methoxyphenyl)amino)methyl)-N,N-dimethylaniline

HRID 2213584Notes

Reaction equation

HRID 2213584 reaction equation
[CH3:1][N:2]([CH3:11])[C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][CH:4]=1.[CH3:12][O:13][C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[CH:16][CH:15]=1>>[CH3:1][N:2]([CH3:11])[C:3]1[CH:10]=[CH:9][C:6]([CH2:7][NH:18][C:17]2[CH:19]=[CH:20][C:14]([O:13][CH3:12])=[CH:15][CH:16]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 74794-(Dimethylamino)BenzaldehydeHCID 7732P-Anisidine

Product 1

HCID 8550754-(((4-Methoxyphenyl)amino)methyl)-N,N-dimethylanilineYield 29.1%

Procedure

By the reaction and treatment in the same manner as in Preparation Example 1 using 4-dimethylaminobenzaldehyde (10.0 g) and 4-methoxyaniline (8.25 g) as starting materials, [(4-dimethylaminophenyl)methyl](4-methoxyphenyl)amine (5 g) was obtained. melting point: 92–94° C.

Workup

  1. customBy the reaction and treatment in the same manner

Sources & evidence

ORD record
ord-850209590aa84c779f6b4dc3bd01bdc2
Source dataset
uspto-grants-2006_09
Patent number
US07105567B2

Reaction notes

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