Indole-3-Carboxaldehyde → [(1H-indol-3-yl)methyl](4-octylphenyl)amine

HRID 2213600Notes

Reaction equation

HRID 2213600 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=O)=[CH:2]1.[CH2:12]([C:20]1[CH:26]=[CH:25][C:23]([NH2:24])=[CH:22][CH:21]=1)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH2:10][NH:24][C:23]2[CH:25]=[CH:26][C:20]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=[CH:21][CH:22]=2)=[CH:2]1

Participants

3

Reactant 2

HCID 10256Indole-3-CarboxaldehydeHCID 853464-Octylaniline

Product 1

HCID 21957882[(1H-indol-3-yl)methyl](4-octylphenyl)amineYield 52.6%

Procedure

By the reaction and treatment in the same manner as in Preparation Example 1 using 1H-indole-3-aldehyde (1.5 g) and 4-octylaniline (2.1 g) as starting materials, [(1H-indol-3-yl)methyl](4-octylphenyl)amine (1.8 g) was obtained.

Workup

  1. customBy the reaction and treatment in the same manner

Sources & evidence

ORD record
ord-acba4362ec39411685203977e029ae06
Source dataset
uspto-grants-2006_09
Patent number
US07105567B2

Reaction notes

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