2,6-Diisopropylphenyl isocyanate → HCID 12972751, compound

HRID 2213609Notes

Reaction equation

HRID 2213609 reaction equation
[CH2:1]([NH:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][OH:20])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:21]([C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH:30]([CH3:32])[CH3:31])[C:25]=1[N:33]=[C:34]=[O:35])([CH3:23])[CH3:22]>>[CH2:1]([N:8]([C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][OH:20])=[CH:11][CH:10]=1)[C:34]([NH:33][C:25]1[C:24]([CH:21]([CH3:22])[CH3:23])=[CH:29][CH:28]=[CH:27][C:26]=1[CH:30]([CH3:32])[CH3:31])=[O:35])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 922592,6-Diisopropylphenyl isocyanateHCID 21957959HCID 21957959, compound

Product 1

HCID 12972751HCID 12972751, compoundYield 23.3%

Procedure

By the reaction and treatment in the same manner as in Example 2 using benzyl[4-(4-hydroxybutoxy)phenyl]amine (1.67 g) and 2,6-diisopropylphenyl isocyanate (1.37 g) as starting materials, 4-{4-[1-benzyl-3-(2,6-diisopropylphenyl)ureido]phenoxy}butanol (0.68 g) was obtained.

Sources & evidence

ORD record
ord-7813aa9953b243dc8b6820747029e3e4
Source dataset
uspto-grants-2006_09
Patent number
US07105567B2

Reaction notes

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