2,6-Diisopropylphenyl isocyanate → N-[(4-chlorophenyl)methyl]-N'-(2,6-diisopropylphenyl)-N-(4-isopropylphenyl)urea

HRID 2213610Notes

Reaction equation

HRID 2213610 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH:9][C:10]2[CH:15]=[CH:14][C:13]([CH:16]([CH3:18])[CH3:17])=[CH:12][CH:11]=2)=[CH:4][CH:3]=1.[CH:19]([C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH:28]([CH3:30])[CH3:29])[C:23]=1[N:31]=[C:32]=[O:33])([CH3:21])[CH3:20]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][N:9]([C:10]2[CH:11]=[CH:12][C:13]([CH:16]([CH3:18])[CH3:17])=[CH:14][CH:15]=2)[C:32]([NH:31][C:23]2[C:22]([CH:19]([CH3:20])[CH3:21])=[CH:27][CH:26]=[CH:25][C:24]=2[CH:28]([CH3:30])[CH3:29])=[O:33])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 922592,6-Diisopropylphenyl isocyanateHCID 21957952N-(4-Chlorobenzyl)-4-isopropylaniline

Product 1

HCID 10298407N-[(4-chlorophenyl)methyl]-N'-(2,6-diisopropylphenyl)-N-(4-isopropylphenyl)ureaYield 50.5%

Procedure

By the reaction and treatment in the same manner as in Example 2 using [(4-chlorophenyl)methyl](4-isopropylphenyl)amine (1.0 g) and 2,6-diisopropylphenyl isocyanate (0.9 g) as starting materials, N-[(4-chlorophenyl)methyl]-N′-(2,6-diisopropylphenyl)-N-(4-isopropylphenyl)urea (0.9 g) was obtained.

Sources & evidence

ORD record
ord-b2b61a9b9e824bcca30f5114246f6cfa
Source dataset
uspto-grants-2006_09
Patent number
US07105567B2

Reaction notes

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