2,6-Diisopropylphenyl isocyanate → HCID 21957883, compound

HRID 2213611Notes

Reaction equation

HRID 2213611 reaction equation
[C:1]([O:4][CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:9][CH:8]=1)(=[O:3])[CH3:2].[CH:21]([C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH:30]([CH3:32])[CH3:31])[C:25]=1[N:33]=[C:34]=[O:35])([CH3:23])[CH3:22]>>[C:1]([O:4][CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([N:13]([CH2:14][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)[C:34]([NH:33][C:25]2[C:24]([CH:21]([CH3:22])[CH3:23])=[CH:29][CH:28]=[CH:27][C:26]=2[CH:30]([CH3:32])[CH3:31])=[O:35])=[CH:9][CH:8]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 922592,6-Diisopropylphenyl isocyanateHCID 21957881HCID 21957881, compound

Product 1

HCID 21957883HCID 21957883, compoundYield 15.8%

Procedure

By the reaction and treatment in the same manner as in Example 2 using 2-(4-benzylaminophenyl)ethyl acetate (5.0 g) and 2,6-diisopropylphenyl isocyanate (5.7 g) as starting materials, 2-{4-[1-benzyl-3-(2,6-diisopropylphenyl)ureido]phenyl}ethyl acetate (1.39 g) was obtained.

Sources & evidence

ORD record
ord-a1371b78131a4968bb6b2f4785b477ad
Source dataset
uspto-grants-2006_09
Patent number
US07105567B2

Reaction notes

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