HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lansoprazole sulfide → Pantoprazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lansoprazole sulfide | HCID 1094080 | — |
| Reactant | Pantoprazole sulfide | HCID 9799341 | — |
| Product | Pantoprazole | HCID 178493214 | 78% |
Reaction Steps
The experiment described in example 2 was repeated using 52.2 g 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl]methyl]thio]-1H-benzimidazole as substrate instead of Lansoprazole sulfide. 42.3 g of crystallized Pantoprazole are isolated after crystallization and drying (yield 78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07105681B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-53b123dc86d9478d986f24aef43d4ee9 |
| Source note | uspto-grants-2006_09 |