HuagongsheHuagongshe Chemistry Print Report · For research reference only
D(-)-Leucinol → (R)-[4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl][3-nitro-4-[[1-(hydroxymethyl)-3-methylbutyl]amino]phenyl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | D(-)-Leucinol | HCID 2724002 | — |
| Reactant | [4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl](4-chloro-3-nitrophenyl)methanone | HCID 10162409 | — |
| Product | (R)-[4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl][3-nitro-4-[[1-(hydroxymethyl)-3-methylbutyl]amino]phenyl]methanone | HCID 60092052 | — |
Reaction Steps
This compound was prepared from the compound of Example 15 and (R)-2-amino-4-methyl-1-pentanol (Aldrich) by the procedure used in Example 57. Mass spectrum (ES) MH+=554.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07105670B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-988dca0278db453c951fc3cc151079d0 |
| Source note | uspto-grants-2006_09 |