HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanamide → 3-{4-Amino-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-thiazole-5-carbonyl}-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanamide | HCID 9864 | — |
| Reactant | 3-(2-Bromoacetyl)benzonitrile | HCID 2735867 | — |
| Reactant | 1-(4-Isothiocyanatophenyl)-4-methylpiperazine | HCID 13718397 | — |
| Product | 3-{4-Amino-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-thiazole-5-carbonyl}-benzonitrile | HCID 21958909 | — |
Reaction Steps
This compound was prepared from cyanamide, 1-(4-isothiocyanato-phenyl)-4-methylpiperazine (of Example 1) and 3-cyanophenacyl bromide (Maybridge Chemical Co. Ltd.) following the procedure used in Example 24. Mass spectrum (ES) MH+=419.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07105670B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-749d8991a6ef45388b41fea13d90ed9a |
| Source note | uspto-grants-2006_09 |