Phenylacetylene → HCID 11435253, compound

HRID 2213963Notes

Reaction equation

HRID 2213963 reaction equation
[CH:1]#[C:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]C.C1(C#C)C=CC=CC=1.[O:17]1[CH:21]=[CH:20][CH:19]=[C:18]1[C:22]#N>C(#N)C1C=CC=CC=1>[C:22]([C:18]1[O:17][CH:21]=[CH:20][CH:19]=1)#[C:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

Participants

5

Reactant 3

HCID 10821PhenylacetyleneHCID 123701-OctyneHCID 692452-Furonitrile

Product 1

HCID 11435253HCID 11435253, compoundYield 62%

Reagents, catalysts & solvents 1

HCID 7505BenzonitrileSolvent

Procedure

The procedure was identical to Example 2, with the exception that 1-octyne (0.590 ml; 0.441 g; 4.00 mmol) was used as a substrate instead of phenylacetylene and 2-furonitrile (0.175 ml; 0.186 g; 2.00 mmol) was used as a substrate instead of benzonitrile. GC analysis of the organic phase of the hydrolyzed reaction sample after 22 h at 65° C. showed the presence of 1.24 mmol (62% yield) of 2-(1-octynyl)furan and no remaining 2-furonitrile in the reaction mixture.

Sources & evidence

ORD record
ord-a99db7caa92b4bbca8c7d841cefe1da7
Source dataset
uspto-grants-2006_09
Patent number
US07105707B2

Reaction notes

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