4-Cyanopyridine → HCID 11229223, compound

Participants

Reaction Steps

The procedure was identical to Example 2, with the exception that 1-octyne (0.590 ml; 0.441 g; 4.00 mmol) was used as a substrate instead of phenylacetylene and 4-cyanopyridine (0.208 g; 2.00 mmol) was used as a substrate instead of benzonitrile. GC analysis of the organic phase of the hydrolyzed reaction sample after 21 h at room temperature showed the presence of 1.60 mmol (80% yield) of 4-(1-octynyl)pyridine and no remaining 4-cyanopyridine in the reaction mixture.

Provenance & Evidence