Phenylacetylene → 2-(3,3-Dimethyl-1-butynyl)furan

Participants

Reaction Steps

The procedure was identical to Example 1, with the exception that 3,3-dimethyl-1-butyne (0.488 ml; 0.329 g; 4.00 mmol) was used as a substrate instead of phenylacetylene and 2-furonitrile (0.175 ml; 0.186 g; 2.00 mmol) was used as a substrate instead of benzonitrile. GC analysis of the organic phase of the hydrolyzed reaction sample after 16 h at 65° C. showed the presence of 1.82 mmol (91% yield) of 2-(3,3-dimethyl-1-butynyl)furan and no remaining 2-furonitrile in the reaction mixture.

Provenance & Evidence