2,5-Dimethoxybenzaldehyde → 2-[(2,5-Dimethoxybenzylidene)amino]-3-methylphenol

Participants

Reaction Steps

2-[(2,5-dimethoxybenzylidene)amino]-3-methylphenol (F7) was prepared in a similar manner for the preparation of 2-[(5-Methoxy-2-methoxymethoxybenzylidene)amino]-3-methylphenol (F4) by using 2,5-dimethoxybenzaldehyde (3.32 g, 20 mmol) instead of 5-methoxy-2-methoxymethoxybenzaldehyde (F1) in 82% (4.44 g): 1H-NMR (400 MHz, CDCl3) δ2.32 (s, 3H), 3.84 (s, 6H), 6.77 (d, 1H, J=7.6 Hz), 6.82 (d, 1H, J=2.0 Hz), 6.83 (d, 1H, J=7.6 Hz), 6.91 (d, 1H, J=9.2 Hz), 6.99 (t, 1H, J=7.6 Hz), 7.06 (dd 1H, J=9.2, 2.0 Hz), 7.69 (s, 1H), 8.94 (s, 1H).

Provenance & Evidence