Benzenesulfonamide, 3-amino- → 4-bromo-2-chloro-N-(3-sulfamoylphenyl)benzenesulfonamide

HRID 221412Notes

Reaction equation

HRID 221412 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[C:4]([Cl:12])[CH:3]=1.[NH2:13][C:14]1[CH:15]=[C:16]([S:20]([NH2:23])(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:13][C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20](=[O:22])(=[O:21])[NH2:23])[CH:15]=2)(=[O:10])=[O:9])=[C:4]([Cl:12])[CH:3]=1

Participants

3

Reactant 2

HCID 7377Benzenesulfonamide, 3-amino-HCID 27347664-Bromo-2-chlorobenzenesulfonyl chloride

Product 1

HCID 269524574-bromo-2-chloro-N-(3-sulfamoylphenyl)benzenesulfonamide

Procedure

Using a method analogous to Method E, using 4-bromo-2-chlorobenzenesulfonyl chloride and 3-aminobenzenesulfonamide, the title compound was obtained as a white solid.

Sources & evidence

ORD record
ord-8312213b25514cd7b358d9d88e7b0aeb
Source dataset
uspto-grants-2012_06
Patent number
US08207167B2

Reaction notes

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