HRID2214269

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6993439

未命名化合物

结构：CC(C)(C)OC(=O)CC(NC(=O)C(Cc1ccccc1)SC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)NC(Cc1cn(C(=O)OC(C)(C)C)c2ccccc12)C(=O)O

HCID69211510

未命名化合物

PRODUCTS

生成物

结构：O=C(O)CC(NC(=O)C(S)Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CO)C(=O)O

HCID10370796

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by condensing H-Ser(But)OBut with the protected dipeptide of Example 88, followed by deprotection and purification by HPLC (40%): (Pos. FAB) ? (MH+).

WORKUP

后处理

customfollowed by deprotection and purification by HPLC (40%)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-27e539143dbc48bf9b77ef68eb8e8853
来源数据集: uspto-grants-2006_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07105539B2
来源说明: uspto-grants-2006_09

反应 SMILES

[NH2:1][C@H:2]([C:9]([O:11]C(C)(C)C)=[O:10])[CH2:3][O:4]C(C)(C)C.C(OC([N:23]1[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[C:25]([CH2:32][CH:33]([NH:37][C:38](=[O:79])[CH:39]([NH:48][C:49](=[O:78])[CH:50]([S:58]C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH2:51][C:52]2[CH:57]=[CH:56][CH:55]=[CH:54][CH:53]=2)[CH2:40][C:41]([O:43]C(C)(C)C)=[O:42])[C:34](O)=[O:35])=[CH:24]1)=O)(C)(C)C>>[C:9]([CH:2]([NH:1][C:34]([CH:33]([NH:37][C:38](=[O:79])[CH:39]([NH:48][C:49](=[O:78])[CH:50]([SH:58])[CH2:51][C:52]1[CH:53]=[CH:54][CH:55]=[CH:56][CH:57]=1)[CH2:40][C:41]([OH:43])=[O:42])[CH2:32][C:25]1[C:26]2[C:31](=[CH:30][CH:29]=[CH:28][CH:27]=2)[NH:23][CH:24]=1)=[O:35])[CH2:3][OH:4])([OH:11])=[O:10]