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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2214666Generated: November 1, 2026

Gamma-Aminobutyric Acid → HCID 54691761, compound

https://huagongshe.com/reaction/2214666

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGamma-Aminobutyric AcidHCID 119—
ReactantFormaldehydeHCID 712—
ReactantHCID 69655692HCID 69655692—
ProductHCID 54691761HCID 5469176155%

Reaction Steps

2-Hydroxy-3-(methyl-naphthalen-1-ylmethyl-carbamoyl)-acrylic acid methyl ester was treated with paraformaldehyde and 4-amino-butyric acid according to the procedure described in the preparation of compound 12 to give the title compound as a white powder (0.0210 g, 55% yield). 1HNMR (300 MHz, CDCl3) δ: 7.93–7.81 (2H, m), 7.55–7.42 (4H, m), 7.42–7.28 (1H, m), 5.13 (2H, s), 4.14 (2H, s), 3.52–3.50 (2H, m), 2.36–2.29 (2H, m), 1.90–1.87 (2H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07109186B2
Source datasetuspto-grants-2006_09
ORD IDord-8efb0ca05e6445f7ad47651e62321b71
Source noteuspto-grants-2006_09