HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N,N',N',N'',N''-Hexamethylmethanetriamine → 2-Di-n-propylamino-8-(1-oxo-2-methoxy-3-(dimethylamino)-prop-2-enyl)-1,2,3,4-tetrahydronaphthalene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N,N',N',N'',N''-Hexamethylmethanetriamine | HCID 79831 | — |
| Reactant | 2-Di-n-propylamino-8-methoxyacetyl-1,2,3,4-tetrahydronaphthalene | HCID 15233538 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-Di-n-propylamino-8-(1-oxo-2-methoxy-3-(dimethylamino)-prop-2-enyl)-1,2,3,4-tetrahydronaphthalene | HCID 54314453 | — |
Reaction Steps
A solution of 2-di-n-propylamino-8-methoxyacetyl-1,2,3,4-tetrahydronaphthalene (1.0 g) and tris(dimethylamino)methane (1.5 ml) in toluene (25 ml) was heated to reflux for 1.5 hours. The reaction was concentrated to give crude 2-di-n-propylamino-8-(1-oxo-2-methoxy-3-(dimethylamino)-prop-2-enyl)-1,2,3,4-tetrahydronaphthalene (1.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05426226 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-d69cbf67c5e94511b5896dc70085b5e5 |
| Source note | uspto-grants-1995_06 |