Sodium → HCID 86588353, compound

Participants

Reaction Steps

Compound 14 (6 g, 5.9 mmol) was dissolved in 40 ml of a toluene/methanol (1/1) mixture). We then added sodium (cat.). After 15 min, the solution was neutralized with Amberlite resin IR 120 (H+), filtered and concentrated. Silica gel chromatography (elution: cyclohexane/ethyl acetate=3/1) of the crude product yielded 16 (5.45 g, 95%) in the form of a colorless syrup.

Provenance & Evidence