Benzenesulfonyl chloride → HCID 5330829, compound

Participants

Reaction Steps

A solution of Compound 17 (5.8 mg, 0.017 mmol), benzenesulfonyl chloride (2.38 μL, 0.019 mmol), triethylamine (2.9 μL, 0.021 mmol) in THF (0.2 mL) and methylene chloride (0.2 mL) was stirred at rt for about 2 hours. The resultant mixture was then separated by chromatography (on silica gel, eluting with 1:1 ethyl acetate:hexane) to give Compound 19 (6 mg, 73% yield).

Provenance & Evidence