Chlorosulfonic acid → HCID 11231761, compound

Participants

Reaction Steps

Chlorosulfonic acid (15 mL) was cooled to 0° C. Then compound 5B (5.5 g. 20.8 mmol) was added over 30 min. The mixture was stirred at RT for 3 h and was poured into ice (100 g). The cloudy solution was extracted with ether (2×100 mL). The extracts were dried with magnesium sulfate and concentrated to give the desired product (4.0 g, 53%) as a yellow oil. The crude product was used immediately for the next step without purification.

Provenance & Evidence