HCID 10195121, compound → 2-(6-((4-Methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methoxy)benzo[b]thiophen-3-yl)acetic acid

HRID 2215104Notes

Reaction equation

HRID 2215104 reaction equation
C[O:2][C:3](=[O:32])[CH2:4][C:5]1[C:6]2[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]3[S:20][C:19]([C:21]4[CH:26]=[CH:25][C:24]([C:27]([F:30])([F:29])[F:28])=[CH:23][CH:22]=4)=[N:18][C:17]=3[CH3:31])=[CH:10][C:7]=2[S:8][CH:9]=1.CC1N=C(C2C=CC(C(F)(F)F)=CC=2)SC=1CSC1C=CC2OC(C(O)=O)=CC=2C=1>>[CH3:31][C:17]1[N:18]=[C:19]([C:21]2[CH:22]=[CH:23][C:24]([C:27]([F:30])([F:28])[F:29])=[CH:25][CH:26]=2)[S:20][C:16]=1[CH2:15][O:14][C:11]1[CH:12]=[CH:13][C:6]2[C:5]([CH2:4][C:3]([OH:32])=[O:2])=[CH:9][S:8][C:7]=2[CH:10]=1

Participants

3

Reactant 2

HCID 10195121HCID 10195121, compoundHCID 20765976HCID 20765976, compound

Product 1

HCID 102171912-(6-((4-Methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methoxy)benzo[b]thiophen-3-yl)acetic acid

Procedure

The title compound was prepared from compound 23D in a manner analogous to compound 6. MS m/z 464 (M+1).

Sources & evidence

ORD record
ord-a405bcda66db4a4eb797e0a6f30084e7
Source dataset
uspto-grants-2006_09
Patent number
US07109222B2

Reaction notes

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