HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 69489709, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-Tert-butyl-4-chloromethyl-5-methyl-oxazole | HCID 21949589 | — |
| Reactant | (2S)-2-ethoxy-3-(4-hydroxy-2-methoxy-phenyl)-propionic acid methyl ester | HCID 68617310 | — |
| Product | HCID 69489709 | HCID 69489709 | — |
Reaction Steps
In analogy to the procedure described in example 46 c], (2S)-2-ethoxy-3-(4-hydroxy-2-methoxy-phenyl)-propionic acid methyl ester was reacted with 2-tert-butyl-4-chloromethyl-5-methyl-oxazole (example 1, step b]) in the presence of cesium carbonate and potassium iodide to yield (S)-3-[4-(2-tert-butyl-5-methyl-oxazol-4-ylmethoxy)-2-methoxy-phenyl]-2-ethoxy-propionic acid methyl ester as colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07109225B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-34a42ad17a184a059a7bf2bd53138f0b |
| Source note | uspto-grants-2006_09 |