HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-5-nitroquinoline → 2-Methoxyquinolin-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-5-nitroquinoline | HCID 21948893 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Methoxyquinolin-5-amine | HCID 12283036 | — |
Reaction Steps
550 mg (2.7 mmol) of 2-methoxy-5-nitroquinoline is stirred in 15 ml of ethyl acetate in the presence of 138 mg of 10% Pd—C for 5 hours in a hydrogen atmosphere. The batch is filtered, and the filtrate is concentrated by evaporation: 520 mg of a light yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07109212B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-bce945398e234458a0bc427c6ba96566 |
| Source note | uspto-grants-2006_09 |