HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(5-Fluoro-2-methoxy-phenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentanal → 4-(5-Fluoro-2-methoxyphenyl)-1-(2-quinolon-5-ylamino)-4-methyl-2-(trifluoromethyl)pentan-2-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(5-Fluoro-2-methoxy-phenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentanal | HCID 11573122 | — |
| Edukt | 5-Amino-1,2-dihydroquinolin-2-one | HCID 15719078 | — |
| Produkt | 4-(5-Fluoro-2-methoxyphenyl)-1-(2-quinolon-5-ylamino)-4-methyl-2-(trifluoromethyl)pentan-2-ol | HCID 21948816 | 60,6% |
Reaktionsschritte
Analogously to Example 20, 226 mg (0.73 mmol) of 4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentanal and 140 mg (0.87 mmol) of 5-amino-2-quinolone are reacted to form 200 mg of the product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07109212B2 |
| Quelldatensatz | uspto-grants-2006_09 |
| ORD ID | ord-8858bcdd6c03457dbd44b0333f26216a |
| Quellennotiz | uspto-grants-2006_09 |