HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21948929, compound → HCID 21948915, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21948929 | HCID 21948929 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 21948915 | HCID 21948915 | — |
Reaction Steps
Under hydrogen atmosphere, a solution that consists of 410 mg (1.67 mol) of 2-(acetoxymethyl)-5-nitroquinoline in 61 ml of acetone can be stirred in the presence of 410 mg of Raney nickel for 2 hours at room temperature. It is suctioned off on Celite and rewashed with acetone. After removal of the solvent and subsequent chromatography on silica gel with hexane-ethyl acetate (10–100%), 230 mg (64% of theory) of the product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07109212B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-12a722f59f714dc5bbcc989cc01640d2 |
| Source note | uspto-grants-2006_09 |