HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21949207, compound → 1-(3-Amino-propyl)-piperidin-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21949207 | HCID 21949207 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(3-Amino-propyl)-piperidin-4-ol | HCID 4712468 | 93.6% |
Reaction Steps
Ethanol (200 ml) and palladium carbon (2.5 g) were added to benzyl N-(3-(4-hydroxypiperidino)propyl)carbamate (2.96 g); and the reaction mixture was stirred vigorously under hydrogen atmosphere overnight. Palladium carbon was removed by filtration, and the filtrate was concentrated to yield the title compound (1.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07109219B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-3b4820da3e76444ca754f3af246c8ff3 |
| Source note | uspto-grants-2006_09 |