HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → N-phenyl-1-(2-phenylethyl)-4-piperidinamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | N-Phenethyl-4-piperidinone | HCID 96437 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | N-phenyl-1-(2-phenylethyl)-4-piperidinamine | HCID 88890 | — |
Reaction Steps
The title compound was prepared by the method outlined in Example 1 using 1-phenethyl-4-piperidone (5.3 g, 0.026 mol), aniline (5.01 ml, 0.55 mol), acetic acid (3 ml) 1,2-dichloroethane (100 ml) and sodium triacetoxyborohydride (5.82 g, 0.027 mol). The title compound was obtained as a white solid (74% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07109310B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-11d7d5afde444838ad946d55ee142e60 |
| Source note | uspto-grants-2006_09 |