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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2215906Generated: October 30, 2026

Potassium Carbonate → HCID 58700277, compound

https://huagongshe.com/reaction/2215906

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant4-(Bromomethyl)pyridineHCID 642799—
ReactantHCID 58700375HCID 58700375—
ProductHCID 58700277HCID 58700277—

Reaction Steps

The title compound was prepared by following the general Method C as a light yellow solid (56 mg, 57%) from (4aS,9bR)-8-hydroxy-5-methyl-6-trifluoromethyl-1,3,4,4a,5,9b-hexahydro-pyrido[4,3-b]indole-2-carboxylic acid tert-butyl ester (Example 71, 100 mg, 0.27 mmol), 4-bromomethyl-pyridine (141 mg, 0.56 mmol) and K2CO3 (156 mg, 1.12 mmol). MS (ESI): 364 (base, M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07109339B2
Source datasetuspto-grants-2006_09
ORD IDord-f4c3673e8d1f4f5fba5cd1faa14935fe
Source noteuspto-grants-2006_09