Ethanolamine → 2-[(1-Ethynylcyclohexyl)amino]ethanol

HRID 2216364Notes

Reaction equation

C(O[C:5]1([C:11]#[CH:12])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1)(=O)C.[CH2:13]([CH2:15][NH2:16])[OH:14]>>[C:11]([C:5]1([NH:16][CH2:15][CH2:13][OH:14])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]1)#[CH:12]

Participants

Reactant 2

HCID 700Ethanolamine

HCID 78903Cyclohexanol, 1-ethynyl-, 1-acetate

Product 1

HCID 147928862-[(1-Ethynylcyclohexyl)amino]ethanol

Procedure

This was synthesized in the same manner as in Production Example 18 except that 1-acetoxy-1-ethynylcyclohexane (Production Example 17) and ethanolamine were used.

Sources & evidence

ORD record: ord-24c1a211e55644e59abd2e5dd5ddd74e
Source dataset: uspto-grants-2006_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07112593B2

Reaction notes

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