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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2216378Generated: October 25, 2026

2-Benzyl-3-iodo-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridine → 2-[[1-[2-Benzyl-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidin-1-yl]-3-pyridyl]ethynylcyclohexyl]amino]ethanol

https://huagongshe.com/reaction/2216378

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Benzyl-3-iodo-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridineHCID 11384307—
Reactant2-[(1-Ethynylcyclohexyl)amino]ethanolHCID 14792886—
Product2-[[1-[2-Benzyl-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidin-1-yl]-3-pyridyl]ethynylcyclohexyl]amino]ethanolHCID 10204226—

Reaction Steps

This was synthesized in the same manner as in Example 6 except that 2-benzyl-3-iodo-6-[(3R,4R)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridine (Production Example 1) and 2-[(1-ethynylcyclohexyl)amino]ethanol (Production Example 20) were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07112593B2
Source datasetuspto-grants-2006_09
ORD IDord-dd582e3741784cdf8a05d5b030dabe01
Source noteuspto-grants-2006_09