HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitrobenzonitrile → 5-Amino-2-(4-morpholinopiperidin-1-yl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitrobenzonitrile | HCID 85504 | — |
| Reactant | 4-Morpholinopiperidine | HCID 795724 | — |
| Product | 5-Amino-2-(4-morpholinopiperidin-1-yl)benzonitrile | HCID 21942389 | 59.9% |
Reaction Steps
By the reaction and treatment in the same manner as in Starting Material Synthetic Example 4 using 2-chloro-5-nitrobenzonitrile (10 g) and 4-morpholinopiperidine (27 g), the title compound (9.4 g) was obtained. melting point: 84-86° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07112594B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-619bc51641ca4e7a878a63b80cfec9be |
| Source note | uspto-grants-2006_09 |