Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2216397Generated: October 30, 2026

Neopentyl glycol → 5-Amino-2-(3-hydroxy-2,2-dimethylpropoxy)benzonitrile

https://huagongshe.com/reaction/2216397

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNeopentyl glycolHCID 31344—
Reactant2-Chloro-5-nitrobenzonitrileHCID 85504—
Product5-Amino-2-(3-hydroxy-2,2-dimethylpropoxy)benzonitrileHCID 2194231859.7%

Reaction Steps

By the reaction and treatment in the same manner as in Starting Material Synthetic Example 2 using 2-chloro-5-nitrobenzonitrile (10 g) and 2,2-dimethyl-1,3-propanediol (5.7 g), the title compound (7.2 g) was obtained. melting point: 194-196° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07112594B2
Source datasetuspto-grants-2006_09
ORD IDord-7c1c405a604348d199c9cada26af5d37
Source noteuspto-grants-2006_09