HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo(b)thiophene-2-carboxylic acid → N-(3-cyano-4-piperidinophenyl)benzo[b]thiophene-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo(b)thiophene-2-carboxylic acid | HCID 95864 | — |
| Reactant | 5-Amino-2-(piperidin-1-yl)benzonitrile | HCID 10845751 | — |
| Product | N-(3-cyano-4-piperidinophenyl)benzo[b]thiophene-2-carboxamide | HCID 21942365 | 29% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 6 using benzo[b]thiophene-2-carboxylic acid (1.7 g) and 5-amino-2-piperidinobenzonitrile (2.0 g), the title compound (1.0 g) was obtained. melting point: 219-245° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07112594B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-a000118ec2f64c37a47e7715ae865d8b |
| Source note | uspto-grants-2006_09 |