HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 21942328, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Acetoxy-2-bromoethane | HCID 13564 | — |
| Reactant | 5-Amino-2-(4-hydroxypiperidin-1-yl)benzonitrile | HCID 21942313 | — |
| Reactant | HCID 21942345 | HCID 21942345 | — |
| Reactant | HCID 69590493 | HCID 69590493 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21942328 | HCID 21942328 | — |
Reaction Steps
By the reaction and treatment in the same manner as in Example 3 using 1-(ethoxycarbonylmethyl)-5-fluoro-2-methyl-indole-2-carboxylic acid (3 g) obtained by reacting 5-fluoro-2-methyl-1H-indole-2-carboxylic acid with potassium carbonate and bromoethyl acetate in dimethylformamide and 5-amino-2-(4-hydroxypiperidin-1-yl)benzonitrile (3.2 g), the title compound (1.4 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07112594B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-9649e4971f744478835522805277ef36 |
| Source note | uspto-grants-2006_09 |