5-Amino-2-neopentyloxybenzonitrile → HCID 21942369, compound

HRID 2216422Notes

Reaction equation

HRID 2216422 reaction equation
[CH:1]([C:4]1[N:9]=[C:8]2[S:10][C:11]([C:13]([OH:15])=O)=[CH:12][C:7]2=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[NH2:16][C:17]1[CH:18]=[CH:19][C:20]([O:25][CH2:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[C:21]([CH:24]=1)[C:22]#[N:23]>>[C:22]([C:21]1[CH:24]=[C:17]([NH:16][C:13]([C:11]2[S:10][C:8]3=[N:9][C:4]([CH:1]([CH3:2])[CH3:3])=[CH:5][CH:6]=[C:7]3[CH:12]=2)=[O:15])[CH:18]=[CH:19][C:20]=1[O:25][CH2:26][C:27]([CH3:29])([CH3:28])[CH3:30])#[N:23]

Participants

3

Reactant 2

HCID 178227345-Amino-2-neopentyloxybenzonitrileHCID 21942346HCID 21942346, compound

Product 1

HCID 21942369HCID 21942369, compoundYield 16.3%

Procedure

By the reaction and treatment in the same manner as in Example 6 using 6-isopropylthieno[2,3-b]pyridine-2-carboxylic acid (2 g) and 5-amino-2-neopentyloxybenzonitrile (1.9 g), the title compound (0.6 g) was obtained. melting point: 244-245° C.

Sources & evidence

ORD record
ord-3ccad82369c84be99b9f141031a2d423
Source dataset
uspto-grants-2006_09
Patent number
US07112594B2

Reaction notes

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