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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2216444Generated: October 26, 2026

5-Methoxyindan-1-one → 2-(6-methoxy-1H-inden-3-yl)propanoic Acid

https://huagongshe.com/reaction/2216444

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methoxyindan-1-oneHCID 78787—
ReactantMethyl 2-bromopropionateHCID 95576—
Product2-(6-methoxy-1H-inden-3-yl)propanoic AcidHCID 2194276968%

Reaction Steps

This substrate was prepared using the same procedures as described for Examples 1 and 2a, starting with 5-methoxyl-1-indanone and methyl 2-bromopropionate. Yield: 68%. 1H NMR (CD2Cl2) δ 7.34 (d, J=9, 1H), 7.07 (d, J=2, 1H), 6.85 (dd, J=9, J=2, 1H), 6.32 (m, 1H), 3.82 (m, 4H), 3.36 (m, 2H), 1.56 (d, J=7, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07112597B2
Source datasetuspto-grants-2006_09
ORD IDord-6ea6d7be246a4ebca88aa6e338572bd4
Source noteuspto-grants-2006_09