Boron Trichloride → HCID 136008554, compound

Participants

Reaction Conditions

Reaction Steps

To a solution 4.1 (83 mg, 0.187 mmol) in CH2Cl2 (2 ml) at −50° C. was added a 1M solution of BCl3 in CH2Cl2 (933 μL, 0.933 mmol) followed by stirring at −50° C. for 15 min, and quenched with MeOH. The mixture was diluted with EtOAc, washed with H2O, sat. NaHCO3, brine, and dried (Na2SO4). Filtration through a 1″ pad of SiO2 and concentration to provided 4.3, 67 mg (100%). MS (ESI) 355.3 (MH+), 353.3 (MH−).

Provenance & Evidence