HRID221659

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4778289

1-(4,6-Dimethyl-2-pyrimidinyl)-4-piperidinamine

C11H18N4

HCID19385010

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(C)nc(N2CCC(NCC(O)COc3cccc(CO)c3)CC2)n1

HCID59819897

未命名化合物

收率 9%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID87082799

未命名化合物

PROCEDURE

实验过程

Synthesis followed SP6 (iPrOH:DMSO 1:1, 120° C., 24 h), using 200 μmol (3-(oxiran-2-ylmethoxy)phenyl)methanol and 1-(4,6-dimethylpyrimidin-2-yl)piperidin-4-amine to give the title compound with 9% yield upon purification by prep. HPLC (reversed phase) and subsequent by prep. TLC (1 mm silica gel, PE/CH2Cl2/MeOH 4:6:1) (LCMS: detected [M+1]=387.2).

WORKUP

后处理

customSynthesis