HCID 21941394, compound → HCID 21941405, compound

Participants

Reaction Steps

Activated MnO2 (9.3 g) was added to the CHCl3 (135 mL) solution of (5,6-dihydro-4H-cyclopenta[b]furan-2-yl)methanol (1.86 g) and refluxed for 1 h under a nitrogen atmosphere. The reaction mixture was filtered through a pad of Celite. The filtrate was concentrated under reduced pressure. The residue was applied to silica gel column chromatography, then the column was eluted with n-hexane-AcOEt (9/1–7/1). The titled compound was obtained as yellow crystals (1.51 g, 77%).

Provenance & Evidence