(2-Chloro-2-oxoethyl)dimethylazanium chloride → {(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}methyl (dimethylamino)acetate

HRID 2216644Notes

Reaction equation

HRID 2216644 reaction equation
[Cl-].Cl[C:3](=[O:8])[CH2:4][NH+:5]([CH3:7])[CH3:6].[CH3:9][C:10]1[CH:14]=[C:13]([CH3:15])[NH:12][C:11]=1/[CH:16]=[C:17]1\[C:18](=[O:28])[N:19]([CH2:26][OH:27])[C:20]2[C:25]\1=[CH:24][CH:23]=[CH:22][CH:21]=2>>[CH3:6][N:5]([CH2:4][C:3]([O:27][CH2:26][N:19]1[C:20]2[C:25](=[CH:24][CH:23]=[CH:22][CH:21]=2)/[C:17](=[CH:16]/[C:11]2[NH:12][C:13]([CH3:15])=[CH:14][C:10]=2[CH3:9])/[C:18]1=[O:28])=[O:8])[CH3:7]

Participants

3

Reactant 2

HCID 21943384(2-Chloro-2-oxoethyl)dimethylazanium chlorideHCID 178424865HCID 178424865, compound

Product 1

HCID 9946572{(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}methyl (dimethylamino)acetate

Procedure

Following the procedure of Example 2, the title compound was prepared from 2-chloro-N,N-dimethyl-2-oxoethanaminium chloride and (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)-methylidene]-1-(hydroxymethyl)-1,3-dihydro-2H-indol-2-one (1).

Sources & evidence

ORD record
ord-5e876e18566d4a0293bdb1006b2a17f0
Source dataset
uspto-grants-2006_09
Patent number
US07112603B2

Reaction notes

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