Carbon Dioxide → 3-Methyl-2-phenylthiophene

HRID 2216725Notes

Reaction equation

HRID 2216725 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4](C(O)=O)[S:5][C:6]=1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.C(=O)=O>>[CH3:1][C:2]1[CH:3]=[CH:4][S:5][C:6]=1[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 280Carbon DioxideHCID 8219144-Methyl-5-phenylthiophene-2-carboxylic acid

Product 1

HCID 104196813-Methyl-2-phenylthiophene

Procedure

The 4-methyl-5-phenyl-2-thiophenecarboxylic acid (127 g, 0.58 mol) prepared as described above was heated to 220–230° C. until the evolution of carbon dioxide ceased. The product was collected and distilled, b.p. 120° C./10 torr. Yield 30.3 g (30%).

Workup

  1. customThe product was collected
  2. distillationdistilled

Sources & evidence

ORD record
ord-5cedf20fa9cf46449fa1ac5645a0cad0
Source dataset
uspto-grants-2006_09
Patent number
US07112638B2

Reaction notes

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